Contrave: Nausea, constipation, headache, insomnia Increased blood pressure and heart rate Other effects: anxiety, dizziness, dry mouth, tremors, risk of seizures in susceptible individuals Serious risks: liver problems, severe allergic reactions, neuropsychiatric events, including mood changes or suicidal thoughts Wegovy: Gastrointestinal issues: nausea, vomiting, diarrhea, constipation, abdominal pain Other effects: fatigue, headache, dizziness (especially during dose escalation) Serious risks: pancreatitis, gallbladder disease, thyroid tumors in high-risk patients, increased heart rate Important: Neither medication is a cure for obesity
The biological mechanisms driving weight regain involve appetite hormones, metabolic adaptation, and underlying genetic predispositions that remain active after medication discontinuation
As glucose levels fall and your insulin needs drop, GLP-1 agonists stop stimulating the production of the hormone
The insurer reviews eligibility, medical necessity, and supporting records
These adverse reactions occurred more commonly on semaglutide tablets than on placebo and occurred in at least 5% of patients treated with semaglutide tablets